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Herbal Extract · Standardised Antioxidant Active

Grape Seed Extract
Vitis vinifera

Vitis vinifera L. · Family: Vitaceae · Seed Extract

A polyphenol-rich grape seed extract standardised to proanthocyanidins NLT 95% — with the assay method declared on every certificate, because OPC figures measured by different methods are not comparable. Prepared from the seed of Vitis vinifera for antioxidant, vascular-support, cosmetic and functional-food formulators. CoA-backed, HPLC-authenticated supply from India.

95% Proanthocyanidins Assay Method Declared Monomer Profile Reported Water-Soluble Halal / Kosher Available CoA-Backed
Grape seed extract powder (Vitis vinifera) standardised to proanthocyanidins 95% — light tan to reddish-brown seed extract, SV Botanica India

Standardised Grade

Vitis vinifera · 95% Proanthocyanidins
95%
Proanthocyanidins
Seed
Part Used
Antioxidant
Functional Class
#40 Mesh
≥95% Passing
36 Months
Shelf Life
Made in India
Country of Origin

What is Grape Seed Extract?

The most method-sensitive assay in the botanical trade — and how we handle it

Grape seed (Vitis vinifera L.) extract is one of the most widely used antioxidant actives in the world, made from a by-product of the wine and juice industries. The seed is unusually rich in proanthocyanidins — condensed tannins built from catechin and epicatechin units — and concentrated extracts deliver that polyphenol load at a controlled specification rather than as a variable agricultural material.

Buying grape seed extract well requires understanding one thing above all others: the number on the certificate depends heavily on how it was measured. Proanthocyanidins are not a single compound but a polymeric series, and at least four assay methods are in common commercial use — DMAC, the Porter (butanol-HCl) method, vanillin, and various total-polyphenol methods such as Folin-Ciocalteu. They measure related but different things, and they return materially different numbers on the same sample.

That is why "95% OPC" from two suppliers can describe two quite different materials, and why some quotations that look competitive are simply using a method that reads high. SV Botanica declares the assay method on every certificate and reports the monomer profile — catechin, epicatechin and gallic acid — by HPLC, which gives buyers a compound-specific anchor that is portable between suppliers in a way an OPC percentage is not.

The second thing to know is that grape seed extract has a well-documented adulteration history, chiefly with peanut skin and pine bark — both cheap, both proanthocyanidin-rich, and the first carrying a genuine allergen consequence. Our authenticity package is built specifically around detecting those.

Active Constituents

The polyphenol series that defines grape seed

Oligomeric Proanthocyanidins

Condensed tannins of two to roughly ten flavan-3-ol units — the oligomeric fraction that gives the extract its name and most of its commercial identity.

Catechin & Epicatechin

The monomeric flavan-3-ol building blocks. Reported by HPLC as a compound-specific anchor that no OPC percentage alone can provide.

Procyanidin B2 & Dimers

Defined dimeric procyanidins used as chromatographic reference points and part of the extract's characteristic fingerprint.

Gallic Acid & Galloylated Units

Grape seed proanthocyanidins carry a characteristic degree of galloylation — a genuine point of difference from pine bark and peanut skin.

Polymeric Proanthocyanidins

Longer chains beyond the oligomeric range. Present in all grape seed extracts; the oligomer-to-polymer balance is a real quality variable.

Total Polyphenols

The wider phenolic pool, sometimes used as an alternative standardisation basis — and a frequent source of specification confusion.

Key Actives & Functional Properties

Why formulators specify a method-declared proanthocyanidin extract

High Standardised Polyphenol Load

Grape seed is among the most concentrated botanical sources of proanthocyanidins available, giving formulators a very high antioxidant load per gram and efficient use of fill volume.

Assay Method Declared

DMAC, Porter, vanillin and Folin methods return materially different figures on the same sample. We state which one produced the number, so your specification means something and quotations become comparable.

Monomer Profile by HPLC

Catechin, epicatechin and gallic acid reported per batch give a compound-specific anchor. Unlike an OPC percentage, these numbers are portable between suppliers and laboratories.

Vascular & Circulatory Positioning

Grape seed OPCs are among the best-recognised botanical actives for vascular and circulatory-support positioning, with strong consumer familiarity in both supplement and cosmetic categories.

Cosmetic Antioxidant Active

The extract is an established cosmetic ingredient for antioxidant and anti-ageing formulations, with good water solubility and a recognised INCI listing.

Water Solubility & Formulation Fit

Water-soluble at typical use levels, suiting beverages, sachets and effervescents as well as capsules and tablets — with astringency the variable to design around.

These are functional and physico-chemical properties of the actives; SV Botanica does not make medical or therapeutic claims for this ingredient.

Grade & Standardisation

Specify the number and the method — one without the other is not a specification

Grade Standardisation Form Best For Solubility
Grape Seed Extract 95% Standard Proanthocyanidins NLT 95% — method declared Light tan to reddish-brown fine powder, ≥95% through 40 mesh Antioxidant & vascular supplements, capsules & tablets Water-soluble
Grape Seed Extract 80% Alternative assay Proanthocyanidins NLT 80% — method declared Light tan to reddish-brown fine powder Cost-tuned blends, multi-ingredient formulas Water-soluble
Grape Seed Extract Polyphenol Basis Polyphenol Total polyphenols NLT 90% (Folin) Reddish-brown fine powder Where a polyphenol claim rather than an OPC claim is required Water-soluble
Grape Seed Extract Low-Monomer Oligomer-rich OPC-enriched, monomer content limited Light tan fine powder Formats where oligomer fraction is specified Water-soluble
Grape Seed Extract Cosmetic Cosmetic Proanthocyanidins to specification, low colour Pale tan fine powder Serums, creams & cosmetic antioxidant actives Water/glycol-soluble

The 95% proanthocyanidin grade is our CoA-backed flagship, supplied with the assay method named on the certificate and the catechin, epicatechin and gallic acid monomer profile reported by HPLC. Please state the required method in your specification — a 95% figure by one method is not equivalent to 95% by another, and comparing quotations without matching the method is the most common error in grape seed procurement. Alternative assay bases, oligomer-enriched and low-colour cosmetic grades, custom mesh and packaging can be quoted against buyer specification and order volume.

Forms Available

Grape Seed Extract is bought in five forms. The standardised extract is the stocked item; granulated and dispersible grades are produced on request and raw botanical forms are sourced against a confirmed order.

FormWhat it isSpecification basisAvailability
Standardised extract powderVitis vinifera seed extract, dried and milledNLT 95% proanthocyanidins, method declaredStocked
Granulated (direct-compression)Extract granulated for tablet linesSame marker, declared on the granuleOn request
Water-dispersible / solubleExtract in a dispersible matrix for beverages, gummies and sachetsMarker declared on the matrix basis; carrier namedOn request
Seed powder (non-extracted)Cleaned Vitis vinifera seed, milled to meshBotanical identity by TLC; heavy metals and microbial panelOn enquiry, subject to lot; phytosanitary certificate usually required
Whole seedCleaned, graded whole seedPurity, moisture, foreign matter; pesticide screenOn enquiry, subject to lot; spice-trade item

A marker percentage without its assay method is not a specification; ask for the method and the plant part on every quotation. Read Grape Seed Extract: A Complete Buyer's Guide, Proanthocyanidins, OPCs and How Grape Seed Extract Is Standardised and Grape Seed Extract Adulteration: Peanut Skin, Pine Bark and How to Detect Them before comparing offers.

Technical Specifications

Full product specification for Grape Seed Extract 95% proanthocyanidins. Values are specification limits, not batch results; a batch-specific CoA is issued per shipment.

ParameterSpecification / LimitMethod
Botanical SourceVitis vinifera L.—
Plant FamilyVitaceae—
Part UsedSeed—
Country of OriginIndia—
AppearanceFine powderOrganoleptic
ColourLight tan to reddish-brown*Organoleptic
OdourCharacteristicOrganoleptic
TasteCharacteristic, astringentOrganoleptic
IdentificationCorresponds to reference extract — positiveBy TLC / HPLC
Assay MethodDeclared per batch (DMAC / Porter / vanillin)Declaration
Proanthocyanidins (% w/w, dry basis)NLT 95.0Method as declared
Total Polyphenols (% w/w)Reported per batchFolin-Ciocalteu
Catechin (% w/w)Reported per batchBy HPLC
Epicatechin (% w/w)Reported per batchBy HPLC
Gallic Acid (% w/w)Reported per batchBy HPLC
Peanut / Pine Bark Marker ScreenNot detectedHPLC fingerprint
Loss on Drying (at 105°C, % w/w)NMT 5.0IP-2014
pH (1% w/v solution)4 – 6IP-2014
Bulk Density (g/ml)NLT 0.35IP-2014
Particle Size (#40 mesh, % w/w)NLT 95Sieve
Total Ash (% w/w)NMT 5IP-2014
Acid Insoluble Ash (% w/w)NMT 1IP-2014
Residual Solvent (Ethanol, ppm)NMT 5,000By GC
Lead (ppm)NMT 1.0ICP-MS
Arsenic (ppm)NMT 1.0ICP-MS
Cadmium (ppm)NMT 0.3ICP-MS
Mercury (ppm)NMT 0.1ICP-MS
Pesticide ResiduesComplies (EU MRL, on request)GC-MS / LC-MS/MS
Ethylene Oxide (ETO)Not treated — declaration providedLC-MS/MS (on request)
Ochratoxin A (ppb)NMT 2HPLC-FLD
Allergen StatusPeanut-free — declaration providedDeclaration
Total Plate Count (cfu/g)NMT 1,000USP <2021>
Yeast & Moulds / Fungi (cfu/g)NMT 100USP <2021>
Escherichia coliAbsentUSP <2022>
Salmonella sp.AbsentUSP <2022>
Staphylococcus aureusAbsentUSP <2022>
CultivationCultivatedDeclaration
Kosher / HalalCertified (on request)Certification
Shelf Life36 months from date of manufacture, in original packed condition—
StorageCool, dry place away from light and moisture, in tightly sealed containers—

*The product is of herbal origin; slight colour variation may occur due to geographical and seasonal variation in the raw material. Proanthocyanidin content is method-dependent and the method is named on every certificate — a figure without its method cannot be compared between suppliers. The catechin, epicatechin and gallic acid monomer profile is reported by HPLC as a compound-specific anchor. Because grape seed extract has a documented adulteration history with peanut skin and pine bark, an HPLC fingerprint screen for those markers and a peanut-free declaration are supplied as standard. Ochratoxin A is tested given the material's origin in the grape processing chain. A current Certificate of Analysis and MSDS are issued with every batch.

Applications by Industry

Where a method-declared proanthocyanidin extract fits

Nutraceutical Supplements

  • Antioxidant & free-radical-defence formulas
  • Vascular & circulatory-support blends
  • Healthy-ageing & longevity formats
  • Eye-health & microcirculation formulas
  • Capsules, tablets & softgels

Cosmetics & Personal Care

  • Antioxidant serums & anti-ageing creams
  • Beauty-from-within supplements
  • Skin-firming & elasticity formulations
  • Natural & clean-beauty lines

Functional Foods & Beverages

  • Antioxidant beverages & shots
  • Effervescents & drink mixes
  • Gummies & chewables
  • Fortified foods & bars

Sports & Active Nutrition

  • Recovery & oxidative-stress formats
  • Circulation & pump formulations
  • Greens & superfood powders
  • Endurance-support blends

Women's & Beauty Nutrition

  • Collagen-support & beauty blends
  • Skin-health supplements
  • Vein-comfort formulations
  • Daily-wellness formats

Private Label & Contract

  • Bulk actives for contract manufacturers
  • Custom specification & method supply
  • Buyer-specified mesh & packaging
  • CoA-backed export shipments

Quality Assurance & Sourcing

From seed to standardised extract — authenticated, tested, documented

Raw Material & Authentication: The extract is prepared from Vitis vinifera seed, a by-product of the grape processing chain. Because grape seed extract is one of the most documented adulteration targets in the botanical trade — peanut skin and pine bark being the classic substitutes — identity is confirmed by TLC and by an HPLC fingerprint screened specifically against those markers, on every batch.

Manufacturing & Testing: Grape Seed Extract is manufactured at certified facilities in India. Each batch runs through a full QC battery — proanthocyanidins by a named and declared method, total polyphenols by Folin, catechin, epicatechin and gallic acid by HPLC, loss on drying, pH, bulk density, ash and acid-insoluble ash, mesh, residual solvent by GC, heavy metals by ICP-MS, ochratoxin A, pesticide residue screening, and a complete USP microbiological panel — before release.

Documentation & Allergen Position: Every shipment is supplied against a batch-specific Certificate of Analysis with an MSDS and a peanut-free declaration. That declaration is not a formality on this ingredient: peanut skin adulteration of grape seed extract is documented, and it would introduce an undeclared major allergen into a finished product. Halal, Kosher and Organic certification are available — see our guides on EU pesticide MRL compliance and EU import requirements for botanical extracts.

Quality & Compliance

What backs every batch of Grape Seed extract

Manufactured at Certified Facilities
Assay Method Declared per Batch
Monomer Profile by HPLC
Peanut & Pine Bark Marker Screen
Peanut-Free Declaration
Identity by TLC
Heavy Metals by ICP-MS
Ochratoxin A Tested
EU Pesticide MRL Screening (on request)
Non-ETO Declaration
USP Microbiological Panel
Halal, Kosher & Organic (on request)
FSSAI Central Licence
APEDA Registered Exporter
Batch-Specific CoA & MSDS

Regulatory & Compliance Notes

Key information for global product registration and labelling

Nutraceutical Use

Used as a botanical active in supplement, functional-food and beverage formats, the extract is supplied to a defined proanthocyanidin specification with the assay method declared. Grape seed extract has a long-established position in supplement markets worldwide and derives from a food-chain by-product, which supports its regulatory position. Buyers remain responsible for determining suitability and for compliance with the relevant food-supplement regulations in their market. This product is not intended to diagnose, treat, cure or prevent any disease.

Allergen & Authenticity

Peanut skin is a documented adulterant of grape seed extract, and undeclared peanut material in a finished product is a serious allergen failure rather than a quality shortfall. We supply a peanut-free declaration as standard and screen the HPLC fingerprint against peanut and pine bark markers on every batch. Buyers with peanut-allergen programmes should treat grape seed extract as a material requiring positive authenticity evidence, not merely a supplier assurance.

Cosmetic Use & Export

Vitis vinifera seed extract is an established cosmetic ingredient with a recognised INCI listing, used in antioxidant and anti-ageing formulations. Supplied from India by SV Botanica — FSSAI Central Licence holder and an APEDA-registered exporter — Kosher certified, against a batch-specific Certificate of Analysis with export documentation on request.

Grape Seed Resources & Guides

Deep-dive articles on grape seed extract for formulators, buyers, and brand owners

Related Products

Frequently co-formulated with Grape Seed Extract in antioxidant, vascular & beauty blends

Frequently Asked Questions

Technical and commercial questions answered by our ingredients team

The flagship grade is standardised to proanthocyanidins at not less than 95% w/w, and — critically — the assay method used is named on every certificate. We also report total polyphenols by Folin-Ciocalteu and the catechin, epicatechin and gallic acid monomer profile by HPLC. An 80% grade, a total-polyphenol-basis grade, an oligomer-enriched grade and a low-colour cosmetic grade are available. Every batch is identity-confirmed and released against a batch-specific Certificate of Analysis.
Because proanthocyanidins are a polymeric series rather than a single compound, and the methods in common commercial use measure related but different things. DMAC responds primarily to certain structural features, the Porter or butanol-HCl method measures acid-catalysed conversion to anthocyanidins, vanillin reacts with particular flavan-3-ol positions, and Folin-Ciocalteu measures total reducing phenolics rather than proanthocyanidins at all. Run on the same sample these return materially different figures. The practical consequence is that a '95% OPC' claim is meaningless without its method, and comparing two suppliers' percentages without matching the method is the single most common error in grape seed procurement. We state the method so the number can be interpreted.
Proanthocyanidins are condensed tannins built from flavan-3-ol units such as catechin and epicatechin. OPC strictly means the oligomeric fraction — roughly two to ten units — as distinct from longer polymeric chains, though in trade practice 'OPC' and 'proanthocyanidins' are often used interchangeably, which is itself a source of confusion. Total polyphenols is a much broader category encompassing all phenolic compounds present, and it will always read higher than a proanthocyanidin figure on the same material. A supplier quoting a total-polyphenol number against a proanthocyanidin specification is offering a higher figure for a less specific measurement. Establish which you are being quoted.
The extract is prepared from the seed of Vitis vinifera L. (family Vitaceae), the common wine and table grape. Grape seed is a by-product of the wine and juice processing chain, which is part of what makes the extract economically attractive. The seed, not the skin, is the proanthocyanidin-rich part — grape skin extract is a different product with a different profile, and the two should not be confused on a specification.
Grape seed extract has one of the best-documented adulteration histories in the botanical trade. The two classic substitutes are peanut skin and pine bark, both cheap, both proanthocyanidin-rich, and both capable of passing a simple OPC assay because that assay measures a compound class rather than a botanical identity. Peanut skin is the more serious problem, because it would introduce an undeclared major allergen into a finished product. We screen the HPLC fingerprint specifically against peanut and pine bark markers on every batch, confirm identity by TLC, report the monomer profile, and supply a peanut-free declaration as standard documentation. Our grape seed adulteration and authenticity guide covers the detection detail.
Yes, with every batch and as standard documentation rather than on request. This matters more here than on most botanicals: peanut skin adulteration of grape seed extract is documented, and undeclared peanut in a finished product is an allergen failure with consequences well beyond a quality deviation. Buyers operating peanut-allergen programmes should treat grape seed extract as a material requiring positive authenticity evidence — a fingerprint screen and a declaration — rather than relying on a general supplier assurance.
Yes, the standard grade is water-soluble at typical use levels, which makes it straightforward in beverages, sachets, effervescents and drink mixes as well as capsules and tablets. The practical variable to design around is astringency rather than solubility: proanthocyanidins bind proteins, which produces the characteristic dry, puckering mouthfeel of tannins and can interact with protein-containing systems. The powder passes not less than 95% w/w through a 40-mesh sieve.
Each batch is identity-confirmed by TLC and by an HPLC fingerprint screened against peanut and pine bark markers. Proanthocyanidins are assayed by a named and declared method, total polyphenols by Folin, and catechin, epicatechin and gallic acid by HPLC. Physico-chemical release testing covers loss on drying, pH, bulk density, ash and acid-insoluble ash and particle size, with residual solvent by GC. Heavy metals are tested by ICP-MS, ochratoxin A by HPLC-FLD given the material's origin in the grape processing chain, and a full USP microbiological panel is run; pesticide residue is screened to EU MRL limits and ethylene oxide by LC-MS/MS on request.
Because grape seed comes from the grape processing chain, and ochratoxin A is a mycotoxin associated with grapes and grape products where storage conditions have allowed mould growth. It is a genuinely relevant contaminant for this raw material in a way it is not for most botanical extracts, and it is regulated in grape-derived products in several markets. We include it as a standard release parameter rather than an on-request extra.
Every batch ships with a batch-specific Certificate of Analysis (proanthocyanidins with method named, total polyphenols, catechin, epicatechin and gallic acid by HPLC, peanut and pine bark marker screen, organoleptic profile, loss on drying, pH, bulk density, ash, mesh, residual solvent, heavy metals, ochratoxin A and microbiology), an MSDS and a peanut-free declaration. Halal, Kosher and Organic certification are available. Country of Origin, non-ETO, non-irradiation, GMO-free, EU pesticide MRL reports and export documentation are provided on request.
Bulk Grape Seed Extract has a shelf life of 36 months from the date of manufacture in original packed condition. Store in a cool, dry place away from light and moisture, in tightly sealed containers. Polyphenols are oxidation-sensitive, so light and air exposure are the practical enemies here — the extract will darken over time in poorly sealed packaging, which is usually a cosmetic change but is also a signal that oxidation is occurring. Re-seal opened containers promptly and avoid extended headspace in part-used drums.
The proanthocyanidin-standardised extract is used across nutraceutical supplements (antioxidant, vascular and circulatory-support, healthy-ageing and eye-health formats), cosmetics and beauty-from-within products, functional foods and beverages including gummies and antioxidant shots, and sports recovery formulations. SV Botanica supplies bulk quantities against buyer specifications with a batch-specific CoA stating the assay method.
We quote EXW, FOB, CIF or CIP to your nominated port or airport — tell us the destination and we will price the landed basis you need. Payment terms are agreed in writing for each order and stated on the proforma invoice; the usual structures are advance payment for first orders and smaller lots, or an irrevocable letter of credit at sight for larger contracts. Bank charges outside India are borne by the buyer and title passes on receipt of full payment. Full commercial terms are set out in our terms and conditions.
Yes, and on this material we recommend specifying both the proanthocyanidin method and an authenticity check in the scope. Every batch ships with a Certificate of Analysis from a NABL-accredited laboratory — India's equivalent of ISO 17025. Buyers can nominate Eurofins, SGS or Intertek for independent pre-shipment testing; ask them to use the same assay method as the supplier certificate, otherwise an apparent discrepancy may be pure method difference rather than a material problem. Analytical methods are listed on our quality page.
Yes. Proanthocyanidin strength, assay method, oligomer-to-polymer balance, monomer limits, colour, carrier, mesh size and pack size can be matched to your formulation — send us your specification, or your current supplier's CoA, and we will confirm what we can produce and at what quantity. If your existing specification does not name an assay method, tell us and we will help you fix that first, because everything else depends on it. Non-standard grades are made against a confirmed order rather than held in stock. We supply in bulk for you to convert or private-label under your own brand; SV Botanica does not sell finished consumer products.
Commercial MOQ for Grape Seed Extract is 25 kg — one standard drum — scaling to full-container loads, with exact MOQ confirmed at quotation. Free evaluation samples of 1–5 kg are dispatched on request. Sample lead time is typically 7–14 business days including documentation, and production lead time on a confirmed bulk order is typically 3–4 weeks plus transit. Send quantities and required dates through our enquiry form.
Yes, against a confirmed order. Non-extracted forms of Vitis vinifera are sourced lot by lot with identity, moisture, foreign matter, heavy-metal and microbial testing reported, and raw botanicals usually need a phytosanitary certificate at destination, which is applied for after packing. They are quoted separately from the extract. Tell us the form, quantity and destination and we confirm availability and lead time before quoting.
Yes, on request. A direct-compression granulated grade is produced for tablet lines and a water-dispersible grade, on a food-grade carrier, for beverages, gummies and sachets. On both, the marker is declared on the granule or matrix basis and the carrier is named on the certificate, so two grades can only be compared when both figures are read together.
No. Enovita and MegaNatural-BP are trademarked ingredients sold by their owners under licence, and SV Botanica does not carry them. What we supply is an unbranded grape seed extract standardised to NLT 95% proanthocyanidins, method declared, with the method stated on the certificate. If your label needs the brand's clinical claims, buy from the brand owner; if you control the specification, a generic extract at the same marker level does the ingredient's job at ingredient pricing.
SV Botanica is a merchant exporter, not the extraction plant. Grape Seed Extract is sourced from GMP-certified extraction facilities in India against SV Botanica's specification, tested batch by batch, and shipped under SV Botanica's own documentation: Certificate of Analysis, MSDS and export paperwork. A buyer searching for a manufacturer gets the same specification control and a single point of accountability, with the added freedom to match each lot to the grade required.
Yes, where the destination authority requires one. Phytosanitary certificates are issued by India's Plant Quarantine organisation against an inspection of the packed consignment, so they are applied for after packing and add a few working days to dispatch. Many importers of processed extracts and oleoresins do not need one; whole and cut botanicals usually do. Tell us the destination and we confirm which certificates apply before the proforma is raised.
Standardised botanical extracts are generally classified in Chapter 13 of the Harmonised System under heading 1302 (vegetable saps and extracts), most commonly 1302.19. The eight-digit Indian ITC-HS line and the tariff line in your market depend on the botanical and the form. The code we declare is printed on the proforma invoice and the export documents; your customs broker makes the final classification for your market.

Source Grape Seed Extract from India's Trusted Exporter

Proanthocyanidin-standardised with the method declared, monomer profile reported, peanut and pine bark screened. Vitis vinifera seed extract, NLT 95%. Samples available for qualified buyers.

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Supplied as a bulk ingredient for further manufacture. Buyers are responsible for compliance with the regulations of their destination market. This product is not intended to diagnose, treat, cure or prevent any disease.