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Nutraceuticals
Quick Specs
FormProvitamin A Carotenoid
Purity20–30% (oil); 10% (beadlet)
SourceDunaliella salina / Palm
Shelf life18–24 months
MOQ1 kg (sample); 5 kg (commercial)
Nutraceuticals

Beta-Carotene

Provitamin A Natural Algal & Synthetic Dunaliella salina E160a Colourant CAS 7235-40-7
The provitamin A carotenoid that converts to retinol on demand — safe at any supplemental dose, impossible to overdose, and backed by decades of clinical data on immune support, skin health, and vision.
Beta-carotene is the body's preferred way to maintain vitamin A status when dietary preformed retinol cannot be safely supplemented — in pregnancy, childhood, and populations at overdose risk. The intestinal enzyme beta-carotene-15,15'-dioxygenase converts beta-carotene to two molecules of retinol, but only when the body needs it. When vitamin A stores are replete, conversion slows to as little as 1:28. This self-regulatory mechanism is unique to provitamin A carotenoids and is the reason no tolerable upper intake level has been set for beta-carotene in non-smokers.

SV Botanica supplies natural Dunaliella salina algal beta-carotene (containing the full cis/trans isomer spectrum), palm-source concentrates, and synthetic water-dispersible beadlets — covering oil suspension grades for softgels and water-dispersible grades for tablets, beverages, and powder blends.
Available specifications
    Quality Assurance

    Dunaliella Algae Source. Provitamin A Potency Verified.

    Every batch tested by HPLC for trans/cis isomer profile, total carotenoid content, heavy metals, pesticide residues, and microbial safety. Nitrogen-flushed, light-protected packaging.

    01

    HPLC isomer profiling

    COA reports all-trans and 9-cis content; confirms carotenoid identity; rules out synthetic adulteration of natural-labelled grades. Total carotenoid assay by UV-Vis also provided.

    02

    Dunaliella salina traceability

    Algae identity, heavy metals, pesticide residues tested; free from marine contaminants and algal toxins; GMP-certified cultivation source documentation provided with each batch.

    03

    Beadlet quality

    Particle size, dispersibility, beta-carotene assay, and moisture per USP/BP specifications. Nitrogen-flushed, light-opaque packaging for both oil and beadlet grades to protect against oxidative degradation.

    04

    Export documentation

    COA, MSDS, Certificate of Origin; FSSAI compliance documentation for food-grade applications; Halal/Kosher certificates on request. Full documentation provided digitally before shipment.

    Formulation Intelligence

    Beta-Carotene Buyer's Guide: Natural vs Synthetic, Safe Dosing & Form Selection

    Beta-carotene occupies a unique regulatory position — it is simultaneously a nutrient, an antioxidant, and a natural food colourant (E160a), making it one of the few nutraceutical ingredients used across supplement, food, and cosmetic categories. Specifying the right grade and form for the application is straightforward once the three key decision points are understood.

    Natural Grade

    Dunaliella salina Algae

    CAS 7235-40-7 · ~50% all-trans + ~50% 9-cis

    Deep orange oil suspension (20% or 30%). Supports "natural beta-carotene" or "from Dunaliella salina algae" label claims. Co-occurring alpha-carotene and xanthophylls provide a full carotenoid spectrum. Research suggests 9-cis isomers may have distinct antioxidant and biological activities not present in all-trans synthetic.

    Best for: premium natural supplements, women's health, prenatal formulations.
    Synthetic Grade

    All-Trans Crystalline / Beadlet

    >97% all-trans · Oil suspension or 10% beadlet

    Available as oil (for softgels) or water-dispersible beadlet 10% (for tablets, beverages, and powders). Lower cost than natural algal grade. No "natural" label claim possible. Identical biological activity to all-trans natural in the dominant isomeric form. Excellent stability in beadlet matrix form.

    Best for: food fortification, beverages, multivitamins where "natural" positioning is not required.
    Dosing Safety

    Standard vs High-Dose

    Safe: 2–6 mg/day · Caution: >20 mg/day in smokers

    For vitamin A equivalence in multivitamins: 2–6 mg/day delivers the RDA equivalent. Safe in non-smokers at 15–30 mg/day for photoprotection. The ATBC lung cancer finding applies ONLY to heavy smokers at >20 mg/day — standard doses in non-smokers carry no documented risk. Label guidance for smokers required at high-dose formulations.

    Note: No upper tolerable intake set by EFSA for non-smokers at standard supplement doses.
    Form Selection

    Oil vs Beadlet

    Oil for softgels · Beadlet for tablets, powders, beverages

    Oil suspension (20–30%) for softgels — best bioavailability when consumed with dietary fat. Beadlet 10% for tablets, powders, and beverages — water-dispersible for flexible manufacturing. Regardless of form, beta-carotene absorption requires co-ingestion with fat. Include vitamin E for shelf life stability.

    Note: Softgels with vegetable oil excipient = maximum bioavailability delivery.
    Buyer FAQ

    Frequently Asked Questions

    Preformed vitamin A accumulates in the liver and can cause toxicity at doses above 3,000µg RAE/day. Beta-carotene conversion to retinol is regulated by vitamin A status — when stores are full, conversion drops to as low as 1:28. This self-regulation makes beta-carotene the preferred provitamin A for prenatal supplements, children, and populations at overdose risk. The EFSA upper tolerable intake for preformed vitamin A is 3,000µg/day; no upper limit is set for beta-carotene in non-smokers due to this self-regulatory mechanism.
    Natural Dunaliella salina beta-carotene contains ~50% all-trans + ~50% 9-cis isomers plus co-occurring alpha-carotene and xanthophylls. Synthetic beta-carotene is >97% all-trans. Research suggests 9-cis may have distinct biological activities. Natural grade supports "from Dunaliella salina" label claims. Both are safe and chemically equivalent in the dominant all-trans form.
    The ATBC and CARET trials found increased lung cancer risk only in heavy smokers (20+ cigarettes/day) taking 20–30mg/day — 10–15× typical dietary intake. The proposed mechanism: pro-oxidant behaviour of beta-carotene in the smoke-oxidised lung environment at pharmacological doses. Standard supplement doses of 2–6mg/day in non-smokers have not been associated with increased cancer risk in any study. Current guidance: avoid >20mg/day beta-carotene supplements for smokers; standard doses remain safe and appropriate for all other populations.
    Oil suspension (20–30%): optimal bioavailability in softgel capsules or food fat matrix. Beadlet 10% (water-dispersible): for tablets, hard capsules, beverages, gummies, and powder blends where oil forms cause manufacturing problems. Key rule: beta-carotene requires fat for intestinal absorption regardless of form — softgels with vegetable oil deliver highest bioavailability. Include vitamin E antioxidant in formulations to protect beta-carotene from oxidation during shelf life.
    For vitamin A equivalence in multivitamins: 2–6mg/day beta-carotene delivers the RDA equivalent (700–900µg RAE). For skin photoprotection: 15–30mg/day in clinical studies. For erythropoietic protoporphyria: 50–150mg/day under medical supervision. Consumer multivitamins: typically 2–6mg. Always formulate with a lipid excipient (softgels with oil) for maximum absorption.