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Nutraceuticals
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Quick Specs
FormTomato Oleoresin
Purity10% (HPLC); >90% synthetic
SourceSolanum lycopersicum (Tomato)
Shelf life18 months (refrigerated)
MOQ1 kg (sample); 5 kg (commercial)
Nutraceuticals

Lycopene

Tomato Oleoresin 5% / 10% / 20% Grades Synthetic >90% Available Singlet O₂ Quencher
Lycopene from tomato oleoresin at 5%, 10% and 20%, with a synthetic crystalline grade above 90%. Highly lipophilic, supplied nitrogen-flushed under cold chain. Specified across the men's-health, cardiovascular and skin supplement categories.
Lycopene is a tetraterpene carotenoid (C₄₀H₅₆) responsible for the characteristic red and pink colour of tomatoes, watermelon, guava, and pink grapefruit. Unlike beta-carotene, lycopene is a pure hydrocarbon carotenoid with no provitamin A activity — its health effects come entirely from its antioxidant and non-antioxidant biological actions. CAS 502-65-8. Commercial lycopene is produced either by solvent extraction from tomato oleoresin (yielding a natural-source lycopene in a tomato oil matrix, typically at 5–20% lycopene concentration) or by synthetic production (identical molecule, >90% purity as red crystalline powder). The tomato oleoresin form dominates the supplement market due to its "natural tomato source" label positioning.

Lycopene's primary mechanism is as a singlet oxygen quencher — it is approximately 100× more effective than vitamin E and 2× more effective than beta-carotene at quenching singlet oxygen radicals. It is specified across the men's-health, cardiovascular and skin supplement categories. Induced singlet oxygen), and arterial walls. SV Botanica supplies lycopene from tomato oleoresin (5%, 10%, 20% concentrations) and synthetic lycopene powder (>90%). Made at GMP/ISO-certified facilities, batch HPLC-tested.
Available specifications
Lycopene 10% Oleoresin
Natural tomato-source, red oleoresin
Lycopene 5% Oleoresin
Standard tomato-source grade
Lycopene 20% Oleoresin
Concentrated natural grade
Synthetic Lycopene >90%
Crystalline powder — same molecule, synthetic route
  • Lipid matrix requirement — highly lipophilic and insoluble in water. The oleoresin grades need an oil carrier; aqueous formats need a beadlet or emulsion system rather than the oleoresin directly.
  • Natural versus synthetic — the tomato oleoresin grades support a natural declaration; the synthetic crystalline grade above 90% is the same molecule at a much higher assay. They are not interchangeable on a botanical label, and the assay basis differs by roughly a factor of nine against the 10% grade.
  • Concentration selection — 5%, 10% and 20% oleoresin grades are available. Fill volume in a softgel is usually the deciding factor: a higher concentration reduces the oil load needed to hit a target inclusion.
  • Cold chain — refrigerated shipping is recommended for oleoresin grades and the 18-month shelf life assumes sealed, cool, nitrogen-flushed storage.
  • Colour carry-through — red to dark red, a strong pigment. It carries into softgel shells and any finished format and will tint an oil base at low inclusion.
  • Synthetic powder format — the crystalline grade at 40–80 mesh suits dry formats where an oleoresin is impractical.
  • Packaging — 5 kg and 25 kg sealed containers with nitrogen headspace for oleoresin, and 1 kg nitrogen-flushed aluminium foil bags for the synthetic crystalline grade. Custom concentrations and pack sizes available.
  • Documentation — each batch ships with a CoA covering assay against the stated grade, heavy metals at NMT 10 ppm with lead at NMT 0.5 ppm, moisture at NMT 1.0% for the synthetic grade, microbial limits, and a source declaration.
Softgel and oil-based supplements
Food and beverage colouring
Carotenoid combination products
Beadlet and emulsion formats
Food fortification
Cosmetic and topical systems
Functional food systems
Private-label and contract manufacture
Common nameLycopene
IUPAC name(6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
Synonymsψ,ψ-Carotene; all-trans-Lycopene; Lycopene tomato extract
CAS number502-65-8
Molecular formulaC₄₀H₅₆
Molecular weight536.87 g/mol
Appearance (oleoresin)Red to dark red viscous liquid/semi-solid
Appearance (synthetic)Bright red crystalline powder
Assay (HPLC)≥10.0% lycopene in oleoresin (or ≥90% synthetic crystalline)
Source (natural grade)Tomato (Solanum lycopersicum) fruit oleoresin
SolubilityInsoluble in water; soluble in chloroform, acetone, petroleum ether; dispersible in oils with heating
LogP (lipophilicity)~15 (extremely lipophilic)
Isomer profile (oleoresin)Predominantly all-trans with 5–15% cis-isomers depending on processing temperature
Moisture (oleoresin)NMT 1.0%
Heavy metalsNMT 10 ppm total; Lead NMT 0.5 ppm; Arsenic NMT 0.5 ppm
Pesticide residuesComplies with EU Regulation 396/2005 MRLs
Microbial limitsTotal aerobic count NMT 10³ CFU/g; Absence of Salmonella, E. coli
Shelf life18 months refrigerated (oleoresin); 24 months (synthetic crystalline)
Storage2–8°C, nitrogen atmosphere, opaque containers, away from light and heat
5 kg and 25 kg sealed containers with nitrogen headspace (oleoresin grade)
1 kg aluminium foil bags (synthetic crystalline grade, nitrogen-flushed)
Refrigerated cold-chain shipping recommended for oleoresin grades
Custom concentrations (5%, 10%, 20%) and pack sizes available
Quality Assurance

Tomato Oleoresin Source. HPLC-Confirmed Lycopene Content.

Every lycopene batch is tested by HPLC for total lycopene content and cis/trans isomer ratio, pesticide residues, heavy metals, and microbial safety. Cold-chain storage and nitrogen-flushed packaging to prevent oxidative degradation.

01

HPLC lycopene quantification with isomer profile

COA reports total lycopene content plus cis:trans isomer ratio by HPLC; both all-trans and cis-isomers are biologically active but differ in bioavailability.

02

Tomato botanical traceability

Raw tomato oleoresin sourced from GMP-certified processors; botanical identity, pesticide residues (EU MRLs), and heavy metals tested on raw material before concentration.

03

Cold-chain storage and nitrogen-flushed packaging

Lycopene is highly sensitive to heat and oxidation; stored refrigerated, nitrogen-flushed, opaque packaging; temperature-controlled export logistics available.

04

Export documentation

COA, MSDS, Certificate of Origin provided with every shipment; Halal/Kosher certificates on request. Full documentation package available digitally before shipment.

Formulation Intelligence

Lycopene Formulator's Guide: Natural vs Synthetic, Isomers & Bioavailability

Lycopene is one of the few nutraceuticals where processing actually improves bioavailability — cooked tomatoes deliver more bioavailable lycopene than raw tomatoes, because heat disrupts the protein-carotenoid matrix and converts the less-bioavailable all-trans lycopene to the more-bioavailable cis-isomers. This counterintuitive fact shapes how commercial lycopene is specified, extracted, and formulated.

Standard Grade

Natural Tomato Oleoresin (10%)

CAS 502-65-8 (all-trans form)

Red viscous oleoresin containing 10% lycopene by weight in tomato oil matrix. The preferred form for softgel manufacturers — the oleoresin's lipid base supports bioavailability and natural label claims. Standard 10% grade means each gram of oleoresin delivers 100mg of lycopene.

Best for: softgel capsules targeting men's health and skin photoprotection.
High Concentration

Concentrated Oleoresin (20%)

20% lycopene in tomato oil matrix

Red viscous oleoresin with 20% lycopene content — used when minimising fill weight per dose is a priority or when the formulation contains competing lipid-soluble ingredients that limit available softgel volume. Slightly higher cost per kg but lower input weight per mg of lycopene delivered.

Best for: combination carotenoid softgels with lutein, zeaxanthin, and astaxanthin.
Pure Form

Synthetic Lycopene Crystalline (>90%)

Identical molecule; no natural label claim

Chemically identical to natural lycopene; bright red crystalline powder. No "natural" label claim possible. Used for: fortified foods and beverages (as a natural-identical colourant), research applications, and markets where natural premium positioning is not required. Lower cost per mg of lycopene. Requires lipid-based excipient in formulation for bioavailability.

Identical biological activity to natural source — supported by EFSA safety opinion.
Bioavailability Tip

Cis vs Trans Isomers

Oleoresin: mixed cis:trans profile

All-trans lycopene (dominant in raw tomatoes) and cis-lycopene (dominant in processed tomatoes and commercial oleoresin) differ in absorption. Cis-isomers are more bioavailable because their bent molecular shape reduces aggregation in intestinal micelles. Commercial oleoresin from heat-processed tomatoes contains a mixed cis:trans profile more favourable than raw tomato. Always specify lycopene in a lipid matrix (softgel with oil) or with a fat-containing meal — lycopene absorption increases 3–4× with dietary fat.

Cold-fill softgel process preserves the cis-isomer profile from oleoresin.
Buyer FAQ

Frequently Asked Questions

Tomato oleoresin at 5%, 10% and 20%, with 10% as the standard grade, plus a synthetic crystalline grade above 90%.
Source and assay. The oleoresin grades support a natural tomato declaration; the synthetic crystalline grade above 90% is the same molecule produced by a synthetic route. Assay differs by roughly a factor of nine against the 10% oleoresin, so they are not comparable on price per kilo and are not interchangeable on a botanical label.
It is insoluble in water and highly lipophilic, dissolving in oils, chloroform and acetone. The oleoresin grades require an oil carrier; aqueous formats need a beadlet or emulsion system rather than the oleoresin directly.
Usually by fill volume. A higher concentration reduces the oil load needed to reach a target inclusion, which matters in softgel formats where capsule size is constrained.
Shelf life is 18 months sealed, cool, refrigerated and nitrogen-flushed, because the material is oxygen- and light-sensitive. Refrigerated shipping is recommended for oleoresin grades and should be specified at enquiry.
Assay against the stated grade, heavy metals at NMT 10 ppm with lead at NMT 0.5 ppm, moisture at NMT 1.0% for the synthetic grade, microbial limits, and a source declaration.
Red to dark red — a strong pigment. It carries into softgel shells and any finished format and will tint an oil base at low inclusion.
5 kg and 25 kg sealed containers with nitrogen headspace for the oleoresin grades, and 1 kg nitrogen-flushed aluminium foil bags for the synthetic crystalline grade. Custom concentrations at 5%, 10% and 20% and custom pack sizes are available.
Against your specification and volume. Concentration, natural versus synthetic, cold-chain requirements and pack size all move the price.

Supplied as a bulk ingredient for further manufacture. Buyers are responsible for compliance with the regulations of their destination market. This product is not intended to diagnose, treat, cure or prevent any disease.