Nutraceutical Ingredient

Vitamin D3
Cholecalciferol

The sunshine vitamin — a fat-soluble secosteroid that regulates calcium homeostasis, bone mineralisation, immune modulation, and gene expression in over 200 human tissues.

CAS 67-97-0 USP / EP Certified Lanolin & Vegan (Lichen) 100K–1M IU/g Oil & Powder Forms
UVB 3-OH 25-OH Liver → 25(OH)D Kidney → 1,25(OH)₂D Bone Ca²⁺ Cholecalciferol · CAS 67-97-0 C₂₇H₄₄O · MW 384.64

Technical Specifications

Full analytical profile for Vitamin D3 oil and spray-dried powder forms

ParameterSpecification

Formulator's Buyer Guide

Form selection, potency options, and key co-formulation considerations

Oil Form

Cholecalciferol in MCT Oil

100,000 IU/g in medium-chain triglyceride carrier. Ideal for softgel fill, oily drops, and lipid-based delivery systems. Clear, pale-yellow oil. Bioavailability enhanced by co-administration with dietary fat. Store refrigerated (2–8°C), nitrogen overlay. Compatible with Vitamin K2 MK-7 oil for D+K combination softgels.

Powder Form

Spray-Dried Microencapsulated

100,000 IU/g and 500,000 IU/g grades. Encapsulated in modified food starch or maltodextrin matrix for enhanced oxidation stability. Free-flowing white powder, D50 150–300μm. Suitable for tablets, capsules, sachets, and dry blends. Reduces light and moisture sensitivity 3–5× vs. unprotected oil. Preferred for solid dose manufacturing.

Vegan Option

Lichen-Derived D3

Sourced from Cladonia rangiferina (reindeer lichen) — the only plant-based natural source of Vitamin D3. Identical molecular structure to lanolin D3. Carries vegan society certification and non-GMO verification. Available in 500,000 IU/g microencapsulated powder. Commands 15–25% premium. Growing demand in plant-based and lifestyle supplement markets.

Stack Synergy

D3 + K2 (MK-7) Combination

D3 increases calcium absorption and osteocalcin production; K2 (MK-7) carboxylates osteocalcin to direct calcium into bone matrix and inhibits vascular calcification. Typical ratio: 1000 IU D3 per 45–90 μg K2 MK-7. Evidence base spans bone mineral density, arterial stiffness, and cardiovascular outcomes. Both are fat-soluble — blend in lipid matrix or encapsulate together for optimal co-delivery.

Quality, Sourcing & Compliance

SV Botanica's Vitamin D3 is sourced from GMP-certified manufacturers with full EU and US registration. Lanolin-derived cholecalciferol is produced via UV irradiation of 7-dehydrocholesterol (7-DHC) isolated from pharmaceutical-grade lanolin. Lichen-derived D3 undergoes chromatographic purification from Cladonia extract. Both sources carry full BSE/TSE-free documentation.

Every batch is assayed by HPLC (UV detection at 265nm) against certified reference standards. Potency verification via UV spectrophotometry confirms IU/g claim. Peroxide value and anisidine value testing ensures oil oxidation status compliance. Heavy metals panel (ICP-MS), microbiological testing, and residual solvent analysis are performed before release.

Regulatory compliance: Vitamin D3 is approved for food fortification (EU Regulation 1925/2006), infant formula (EU Delegated Regulation 2016/127, max 3.0 μg/100 kcal), and dietary supplements. GRAS status confirmed (FDA 21 CFR 184.1950). CoA, MSDS, Allergen Declaration, BSE/TSE statement, and Non-GMO affidavit supplied with every shipment.

Frequently Asked Questions

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Oil and powder forms, lanolin and lichen sources, custom potencies available. Technical documentation provided.

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