What Is Licorice Extract?

Licorice extract is a concentrated preparation made from the root and stolon of Glycyrrhiza glabra L., a legume of the Fabaceae family. In Ayurveda it is yashtimadhu or mulethi; in European and Chinese traditions it is equally long-established, and it appears in more pharmacopoeial monographs than almost any other root.

The name is literal. Glykys rhiza is Greek for "sweet root", and the sweetness is glycyrrhizin — a triterpene saponin roughly fifty times sweeter than sucrose. Glycyrrhizin is simultaneously the marker compound, the sensory signature, and the reason licorice carries a regulatory profile most botanicals do not.

The Three Grade Families — Get This Right First

This is the section that matters most. "Licorice extract" describes three commercially distinct materials:

Grade familyGlycyrrhizin specStandardised onTypical use
Standardised extractNLT 10% / 20% / 25%Glycyrrhizin (HPLC)Digestive, respiratory, confectionery, beverages
DGL (deglycyrrhizinated)NMT 2%Flavonoid fraction retainedGastric-comfort supplements at higher daily dose
Glabridin (cosmetic)Not the basisGlabridin NLT 40% (HPLC)Skin-brightening and even-tone actives
Native ratioNot declaredExtract ratio 4:1 / 10:1Traditional and Ayurvedic formats

Note that the first two rows carry inverted specifications for the same compound. A buyer who writes "licorice extract, glycyrrhizin specification per attached" and attaches a DGL sheet to a supplier quoting standardised material has created a contradiction that someone will resolve badly.

Buyer tip: name the grade family explicitly in the first line of your enquiry — "DGL grade, glycyrrhizin NMT 2%" or "standardised grade, glycyrrhizin NLT 20% by HPLC". Do not rely on the phrase "licorice extract" plus a price to communicate which of three materials you want. The glabridin grade in particular is a different price bracket entirely, and quoting it against a standardised specification produces a number that looks like a mistake because it is.

The Glycyrrhizin Ceiling: Why Licorice Needs Extra Arithmetic

Licorice is one of the few botanicals with a broadly recognised intake ceiling. Sustained high glycyrrhizin intake is associated with pseudoaldosteronism — potassium loss, sodium and water retention, and raised blood pressure — and international scientific opinion has converged on roughly 100 mg of glycyrrhizin per day as a level below which adverse effects are not expected in most healthy adults.

Two practical consequences for a buyer:

  1. Your dose arithmetic runs on the assayed percentage, not the grade name. A "20% grade" that assays at 24% delivers 20% more glycyrrhizin per serving than you planned. For a marker with a ceiling, that direction of variance is the one that matters. Insist the CoA states the measured figure, not the nominal grade.
  2. Several markets require an advisory statement above defined thresholds in confectionery and beverages, warning that people with hypertension should avoid excessive consumption. Whether you cross that threshold is a calculation on your finished product, and it needs a real ingredient number as its input.

This is precisely why DGL exists. If your format needs a meaningful daily dose of licorice's flavonoid fraction, removing the glycyrrhizin removes the ceiling — that is the whole commercial logic of the grade.

Species Matters More Here Than for Most Roots

Three Glycyrrhiza species are pharmacopoeially recognised in different parts of the world:

All three contain glycyrrhizin, so a glycyrrhizin assay alone cannot distinguish them. That is an unusual and important gap: on most botanicals the marker assay doubles as a species check, and here it does not. The flavonoid profile does distinguish them — glabridin is characteristic of G. glabra — which is why a species declaration plus a TLC identity matters, and why a cosmetic buyer specifically cannot treat the species as interchangeable. We cover the mechanics in licorice adulteration and authenticity.

What a Genuine Licorice Extract CoA Must Show

These are the specification limits SV Botanica supplies a standardised licorice root extract against.

ParameterSpecification / LimitMethod
Species declarationGlycyrrhiza glabra L., root and stolonDocumentation
IdentificationCorresponds to glycyrrhizin — positiveBy TLC
Glycyrrhizin (standardised grade)NLT 20% w/w (dry basis) — measured figure statedBy HPLC
Glycyrrhizin (DGL grade)NMT 2% w/wBy HPLC
Glabridin (cosmetic grade)NLT 40% w/wBy HPLC
Loss on drying (105°C)NMT 5.0%IP-2014
Total ash / acid-insoluble ashNMT 10% / NMT 2%IP-2014
Particle size (#40 mesh)NLT 95% w/wSieve
Residual solvent (ethanol)NMT 5,000 ppmBy GC
Lead / Arsenic / Cadmium / MercuryNMT 1.0 / 1.0 / 0.3 / 0.1 ppmICP-MS
Pesticide residuesComplies (EU MRL, on request)GC-MS / LC-MS/MS
Ethylene oxideNot treated — declaration providedLC-MS/MS (on request)
Microbiology (TPC / Y&M / pathogens)NMT 1,000 / NMT 100 / negativeUSP <2021>/<2022>
Shelf life36 months from manufacture

Licorice is a deep-rooted perennial, which makes the heavy-metal block worth particular scrutiny — the plant draws from a larger soil volume over more seasons than an annual crop. Acid-insoluble ash matters for the same reason, catching soil carry-over as well as mineral bulking.

A Handling Note Buyers Underestimate

The standard glycyrrhizin-standardised grade is markedly hygroscopic — it is a saponin- and sugar-rich water-soluble powder, and it will pick up moisture from humid air and cake. This is the most common practical complaint with the material and it is entirely preventable: keep containers tightly sealed, re-seal promptly after part-use, and do not store opened drums in an uncontrolled warehouse through a monsoon or a humid summer. Caked material is usually still on specification, but it is a nuisance in a dosing line.

Why Source Licorice Extract from India?

India has a long cultivation and processing tradition for G. glabra, a mature export-oriented extract manufacturing base, and the analytical infrastructure — NABL-accredited laboratories, HPLC standardisation as routine — built for regulated markets. Sourcing directly brings species-authenticated glabra material rather than an unspecified Glycyrrhiza, manufacturer-direct pricing, and per-batch documentation covering ETO, irradiation and GMO status.

What to Ask Your Supplier

  1. Grade family confirmed in writing: standardised, DGL, glabridin or native ratio
  2. Batch-specific CoA stating the measured glycyrrhizin percentage, not the nominal grade
  3. Species declaration — Glycyrrhiza glabra specifically, not "licorice"
  4. TLC/HPLC identity confirming correspondence with reference material
  5. Glabridin figure where a cosmetic grade or a species check is needed
  6. Heavy-metal report by ICP-MS with numeric limits for Pb, As, Cd, Hg
  7. Acid-insoluble ash, residual solvent and declared carriers
  8. Pesticide residue report against EU MRL, and a non-ETO declaration
  9. Declarations: non-irradiated, GMO-free, allergen status

Our companion licorice extract supplier evaluation guide turns this into a scored checklist. SV Botanica supplies standardised, DGL, glabridin and full-spectrum licorice root extract from certified manufacturing facilities in India, with full documentation available before any bulk commitment.